Fight Coronavirus, Start by Practicing Hand Hygiene

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The recent coronavirus outbreak has sparked fear and people are finding ways to protect themselves. So, what exactly are the measures that work? Medical experts urge the public to practice hand hygiene and those that are sick to wear a mask. For healthy individuals, clean hands are far more effective in keeping the virus away compared to wearing masks.

Why Is It Important to Maintain Hand Hygiene?

As the hands are a significant medium for pathogen transfer, practicing hand hygiene is a lifetime habit to stay healthy. The spread of coronavirus is now an international concern and every individual should do their part to minimize it’s transmission rate.

Effective Hand Hygiene Practice

Dr Kalisvar Marimuthu, senior infectious disease consultant at the National Centre for Infectious Diseases (NCID) mentioned that the best way to keep hands clean is to wash them with soap. However, in the occasion where soap and water are not available, hand sanitizers with at least 60% of alcohol is an alternative.  For people that uses wet wipes, it is crucial to ensure that the wipes consist of at least 40% of alcohol for effective cleaning.

High Demand for Hand Hygiene Products

Because of the current outbreak of coronavirus, hand sanitizers are in high demand and are sold out in majority of the stores. There will be recurring and emerging diseases in the future and it is important for manufacturers to create sufficient amounts of products with the effective dosage of anti-bacterial component. One problem that consumers face is that these products are drying to the skin. So, to encourage frequent hand washing and proper hand hygiene, companies should offer products that are mild yet effective.

Formulation Guide: Mild Hand Wash

Phase Material Function INCI Name Supplier % w/w
A
Tetrasodium EDTA
Chelating Agent
Tetrasodium EDTA
-
0.1
Glycerin
Emollient
Glycerin
-
3.0
Propylene Glycol
Emollient
Propylene Glycol
-
1.5
Solvent
Water
-
64.2
B
Main Surfactant
Cocamidopropyl Betaine
Maha Chemicals
15.0
Secondary Surfactant
Lauryl Glucoside
Maha Chemicals
10.0
Co-Surfactant
Sodium Cocoyl Alaninate
Sino Lion
5.0
C
DMDM Hydantoin
Troy
0.5
D
NaCl
Thickener
Sodium Chloride
-
0.7
E
Citric Acid
pH Adjuster
Citric Acid
-
qs

Procedures

  1. Predisperse phase A in room temperature
  2. Add phase B to phase A and mix until homogeneous
  3. Add phase C & D step by step while mixing
  4. Adjust pH with citric acid solution until pH 6-7

End Product Properties

Property Results
Appearance
Clear viscous liquid
pH
6.60
Viscosity, cps
3720 (25℃, Brookfield RVT, 12rpm, 3#spindle)

Formulation Guide : Hand Sanitizer

Phase Material INCI Name Supplier % w/w
A
Ethanol (95%)
Ethanol (95%)
-
65.0
Deionized Water
Deionized Water
-
30.54
Aloe Vera Extract
Aloe Barbadensis Leaf Extract
TEN
2.0
SuperGel CE
Carbomer
Sino Lion
0.6
B
2-amino-2-methyl-1-propanol
ANGUS
0.36
C
Sino Japan
1.2
D
Fragrance
Fragrance
-
0.3

Procedures

  1. Disperse Carbomer into phase A and stir to mix well
  2. Neutralize with phase B under agitation
  3. Add Phase C under agitation
  4. Add phase D under agitation, and then obtain the product.

End Product Properties

Property Results
Appearance
Clear gel
pH
6.0 - 6.5
Viscosity, cps
13000~18000Pa.s (25℃, Brookfield RVT, 20rpm, 6#spindle)

Carbomer Shortage? Use CELQUAT® SC-230M or Maha Flow 100 Instead!

Formulation Guide : Hand Sanitizer with CELQUAT® SC-230M

Phase Material INCI Name Supplier % w/w
A
CELQUAT SC-230M polymer
Polyquaternium-10
AkzoNobel Global Personal Care
2.0
Deionized Water
Deionized Water
-
31.75
SD Alcohol 40-A
Denatured Alcohol
-
65.0
Glycerin
Glycerin
Maha Chemicals
1.0
Fragrance
Fragrance
-
0.25

Procedures

  1. Add CELQUAT SC-230M polymer to the deionized water and half of the denatured alcohol. Mix, using moderate agitation, until solution thickens.
  2. Add the remaining amount of denatured alcohol and increase the level of agitation to high. Mix until homogeneous.
  3. Pre-mix glycerin and fragrance. Add to the batch and mix until homogeneous.

End Product Properties

Property Results
Appearance
Clear gel
pH
6.5 - 7.0
Viscosity, cps
8,500 – 12,500 cps (RVTD, Spindle 4, 20 rpm)

Formulation Guide : Hand Sanitizer with Maha Flow 100

Phase Material INCI Name Supplier % w/w
A
Deionized Water
Deionized Water
-
q.s. to 100.00
Ethanol
Ethanol
-
62.0
Acrylates/Beheneth-25 Methacrylate Copolymer
Maha Chemicals
6.40
NaOH (10% w/w)
Sodium Hydroxide
-
q.s.
Glycerin
Glycerin
Maha Chemicals
1.0
Fragrance
Fragrance
-
0.25

Procedures

  1. Mix water with Maha Flow 100 and agitate at 500 rpm for more than 20 minutes.
  2. Add ethanol during agitation.
  3. Add NaOH drop by drop slowly until desired pH is achieved.
  4. Add Glycerin and fragrance

End Product Properties

Property Results
Appearance
Clear gel
pH
6.5 - 7.0
Viscosity, mPa.s
2600

Solutions for Alcohol Shortage

Formulation Guide: Water-Based Hand Sanitizers

Phase Material INCI Name Supplier % w/w % w/w
A
Propylene Glycol
Propylene Glycol
-
5.0
5.0
Glycerin
Glycerin
-
5.0
5.0
Water
-
q.s. to 100.0
q.s. to 100.0
B
Chlorohexidine Gluconate
Maha Chemicals
4.0
-
Benzalkonium Chloride
Maha Chemicals
-
1.65
C
TEN
1.0
1.0
Chamomille Recutita (matricaria) Flower Extract, Butylene Glycol
TEN
1.0
1.0
D
AMP ULTRA PC 2000
2-amino-2-methyl-1-propanol
Angus
q.s.
q.s.

Procedures

  1. Predisperse phase A in room temperature
  2. Add phase B and phase C while mixing
  3. Adjust pH to 6 – 7.5 with AMP Ultra PC 2000 if necessary

End Product Properties

Property Results
Appearance
Clear – Slightly hazy liquid
pH
7.0 - 7.5

A clean hand is a caring hand

Encourage consumers to practice hand hygiene now!! Contact us for free samples!!

 

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