How to tackle uprising issue of isothiazolinone-based preservatives?

Itchy Skin MahaChem

Moving away from isothiazolinone-based preservatives, what are your future alternatives which are cost-effective?

Methylisothiazolinone (MIT) and Benzisothiazolinone (BIT) are two of the most common preservatives found in cleaning products such as laundry and dish detergents. Isothiazolinone-based preservatives are proven to protect wide range of formulations against bacterial and fungal growth effectively at low cost. However, isothiazolinone-based preservatives have also been linked to many potential problems such as skin allergic reactions and safety issues. With a stricter EU regulation on skin allergic issues, Europe is banning MIT-based preservatives from Home, Industrial and Institutional Care Products by 2020.

On the other hands, BIT supply has been an issue since the first China chemical plant explosion in 2015. The recent chemical plant explosion in China causes a further shortage in supply of BIT-based preservative. This leads to price increase by 1.5 times of the original price.

With a greater awareness that isothiazolinone-based preservatives will soon be discontinued, manufacturing companies should consider the replacement of both BIT and MIT. To those formulators who are in need of replacing BIT and MIC, we offer you a preservative grade that is globally approvedTroyguard 44 preservative.

Our Solution: Troyguard 44

Troyguard 44 is a water-soluble preservative solution to protect water-based homecare formulations from bacterial and fungal growth at low dosage.

Troyguard 44 consist of 50% Sodium N-(Hydroxymethyl) glycinate which is derived from glycerin, a natural occurring amino acid.

Features and Benefits of Troyguard 44

Features and Benefits
Effective at 0.05-0.15%
  • With only 0.05% dosage, Troyguard 44 inhibit bacteria growth in 2 days
Cost effective
  • Lower dosage required as compared to Isothiazolinone-based preservative.
Compliant with Ecocert Detergent Standard
  • Glycerin derived from natural source
  • Troyguard 44 manufacture via Eco-friendly process
  • Excellent choice for formulators looking to produce green cleaning products
Broad Spectrum preservative
  • Effective against wide range of microorganisms over wide pH range (3-12)
  • Good stability at high temperature and wide pH range (3-12)


Troyguard 44 can be used for the number of applications including:

  • Degreasers
  • Laundry care
  • Wet wipes
  • Polisher
  • Multi-purpose and specialty cleaners

Formulation guides

Facial Toner


A Water Solvent Water Add to 100
A Tetrasodium EDTA Chelating Agent Tetrasodium EDTA Brataco 0.05
A Niacinamide Whitening Niacinamide 0.5
A Butylene Glycol Humectant Butylene Glycol 3
A Glycerine Humectant Glycerine 5
B Calnomix Anti-inflammation Chamomilla Recutita (Matricaria) Flower Extract, Acer saccharum (Sugar Maple) Extract, Portulaca Oleracea Extract, Butylene Glycol T.E.N. 0.8
B Witch Hazel Extract IN-BG Astringent Hamamelis Virginiana (Witch Hazel) Leaf Extract, Butylene Glycol T.E.N. 1
B Evening Primrose Extract IN-BG Brightening, Moisturizer Oenothera Biennis (Evening Primrose) Flower Extract & Butylene Glycol T.E.N. 0.7
B Aloe Vera Extract BG Moisturizer Aloe Barbadensis Extract, Butylene Glycol TEN 0.3
C Parfume Parfume Mixing Compounds 0.05
C Alkest CSO 400H Solubilizer PEG 40 Hydrogenated Castor Oil Oxiteno 0.05
D Lactic Acid / Citric Acid pH Adjuster Lactic acid acid / Citric
E Troyguard 44 Preservative (Anti fungal) Sodium N (hydroxymethyl) glycinate,water Troy 0.1
Total 100


  1. Mix phase A until the solution becomes homogenous at room temperature
  2. Add phase B step by step to phase A at room temperature
  3. Pre-disperse phase C at room temperature, then add to bulk no.2 in temperature 40℃-50℃, mix until it becomes homogenous
  4. Add phase E and mix until it becomes homogenous
  5. Adjust the pH in range 5,5 – 6,5, continue to do cooling

End Product Appearance

Parameter Standard Result
Appearance Clear Liquid – Slightly yellowish Slightly Yellowish
pH 5,5 – 6,5 5,88

Have you made up your mind?

Our Troyguard 44 preservative is eco-certified and easy to be used in many home care formulations. Furthermore, with small dosage level (only 0.05%), the preservative can effectively resist bacterial growth for two days. If you are interested in this product, please find out more via product link below.

Ecocert Detergent Standard broad specturm preservative.

Related Posts